Just three days after Trend Micro had notified Adobe of a 0-day vulnerability in their Flash player, Adobe addressed the flaw with a patch. APSB15-27 provides fixes for three vulnerabilities, and one of them, CVE-2015-7645, is currently being used in attacks in the wild. You should apply the update as quickly as possible as we expect the exploit to show up in ExploitKits soon, which will greatly increase the number of attacked machines.
Try to be quicker than Adobe and apply the patch in under three days.
For technical background of the vulnerability, take a look at Trend’s follow up blog post.